Can I use a SRAM Eagle™ 12-speed chain on an SRAM RED® XG-1290 cassette? February 06, 2019 15:20 No. Eagle™ chains are only compatible with Eagle™ cassettes. Related articles Will a new RED® road chain work on a SRAM Eagle™ drivetrain? What chain lubes do you recommend for new SRAM RED and Force road chains? Can I use the eTap AXS rear derailleur without the front derailleur to make a 1x drivetrain? Is a special chain tool required for new RED and Force eTap AXS™ road chains? Will a new SRAM RED AXS™ road chain work on a SRAM Eagle™ drivetrain?